TB-500

10 mg

$69.99 CAD

A research peptide discussed alongside thymosin beta-4 biology, where the cited evidence comes from mouse wound-repair models.

Format: 10 mg
Use: Laboratory research

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For laboratory research only · Not for human consumption

What is TB-500?

TB-500 is a research material whose name is associated with thymosin beta-4 and with a shorter synthetic peptide containing that protein’s actin-binding domain. Which molecular form a given vial contains is a supplier-specified detail that should be confirmed from documentation rather than inferred from the name.

Key concepts: Mass spectrometry (MS) · Purity · In vivo

How it works and what researchers study

The relevant literature examines actin-binding thymosin biology in wound-repair models, often in animals with impaired healing, because those models make changes in repair easier to detect.

What the evidence shows

Published work reported that thymosin beta-4 and a synthetic peptide containing its actin-binding domain promoted dermal wound repair in diabetic and aged mice.

Limits of the evidence

Mouse wound models are animal evidence; they are not clinical proof in people.
The cited work does not establish that a TB-500 vial is full-length thymosin beta-4. Independent analytical work has identified the short N-acetylated Ac-LKKTETQ fragment in a TB-500 product examined in a laboratory, which shows why identity must be confirmed per lot rather than inferred from the name.
Sequence and registry identifiers should come from supplier documentation. Where they are not stated, treat them as unknown rather than assumed.

References

Philp D et al. Thymosin beta 4 and a synthetic peptide containing its actin-binding domain promote dermal wound repair in db/db diabetic mice and in aged mice. Wound Repair Regen. 2003. doi:10.1046/j.1524-475x.2003.11105.x View source
Characterization of a TB-500 product by chromatography and mass spectrometry identified the N-acetylated thymosin beta-4 (17-23) fragment Ac-LKKTETQ. Drug Test Anal. 2012. doi:10.1002/dta.1402 View source
Analytical detection study of the thymosin beta-4 fragment Ac-LKKTETQ and its metabolites in equine samples. J Chromatogr A. 2012. doi:10.1016/j.chroma.2012.09.043 View source

Compound science vs product quality

The research described here studied the compound under laboratory or clinical conditions. No cited paper or label tested a Proof Line Peptides vial. Product-level questions — identity, stated quantity and lot-matched documentation — are answered by records supplied with the material, not by published studies.

Questions about TB-500

Is TB-500 identical to thymosin beta-4?: Not necessarily. The literature covers both the full-length protein and a shorter actin-binding-domain peptide, so identity is a documentation question.
Does the mouse research apply to human healing?: It does not establish human outcomes. Impaired-healing mouse models support mechanistic hypotheses and further study.
What should I check before ordering?: The named molecule, stated quantity, lot identifier, any lot-matched analytical report with its methods, and the product-specific storage instructions.